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INSRR Polyklonaler Antikörper

INSRR Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55112-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse kidney tissue using INSRR Polyclonal antibody (55112-1-AP)

    WB analysis of mouse kidney using 55112-1-AP (same clone as 55112-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human brain tissue using INSRR Polyclonal antibody (55112-1-AP)

    WB analysis of human brain using 55112-1-AP (same clone as 55112-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55112-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55112-1-PBS bindet in WB, Indirect ELISA INSRR und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name IR related receptor
Berechnetes Molekulargewicht 144 kDa
Beobachtetes Molekulargewicht 150-155 kDa
GenBank-ZugangsnummerNM_014215
Gene symbol INSRR
Gene ID (NCBI) 3645
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.