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IPO8 Polyklonaler Antikörper

IPO8 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32476-1-PBS

Synonyme

Imp8, Importin-8, Ran-binding protein 8, RanBP8

Filter:
  • Western Blot (WB) analysis of various lysates using IPO8 Polyclonal antibody (32476-1-AP)

    WB analysis using 32476-1-AP (same clone as 32476-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32476-1-AP (IPO8 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32476-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32476-1-PBS bindet in WB, Indirect ELISA IPO8 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IPO8 fusion protein Ag35395
Vollständiger Name importin 8
Beobachtetes Molekulargewicht120-125 kDa
GenBank-ZugangsnummerBC167853
Gene symbol IPO8
Gene ID (NCBI) 10526
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IPO8(Importin 8) is a gene encoding protein, which is located on human chromosome 12. It belongs to the nuclear protein transport family, and is mainly involved in the process of nuclear protein introduction. IPO8 regulates the transport function of nuclear pore complex by interacting with Ran GTPase and other proteins (PMID: 11682607). It is expected to be located in the cytoplasm and nucleus. IPO8 is associated with many diseases, including VISS syndrome and Loeys-Dietz syndrome. These diseases usually involve cardiovascular defects, skeletal abnormalities and immune loss. The molecular weight of PO8 protein is about 125kDa, and its structure includes helix and β-sheet. It has a specific three-dimensional structure and can form complexes with other protein.