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IQCG Polyklonaler Antikörper

IQCG Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33459-1-PBS

Synonyme

DRC9, Dynein regulatory complex protein 9, IQ domain-containing protein G

Filter:
  • Western Blot (WB) analysis of various lysates using IQCG Polyclonal antibody (33459-1-AP)

    WB analysis using 33459-1-AP (same clone as 33459-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33459-1-AP (IQCG antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33459-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33459-1-PBS bindet in WB, Indirect ELISA IQCG und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IQCG fusion protein Ag37506
Vollständiger Name IQ motif containing G
Berechnetes Molekulargewicht 51 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC004816
Gene symbol IQCG
Gene ID (NCBI) 84223
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human IQ motif containing G (IQCG) gene was first reported to be involved in the chromosome translocation in a case of acute T-lymphoid/myeloid leukemia. The expression of Iqcg is prominently enriched in the testis of mice and reveals an ordered expression pattern during spermatogenesis. Iqcg knockout (KO) mice are sterile, due to the severe malformation and total immobility of their spermatozoa. The axoneme in the KO sperm flagellum is disorganized and hardly any typical normal "9+2" pattern, composed of two central microtubules surrounded by nine microtubular doublets, could be found in the KO spermatids. However, the cilia structures in the trachea and oviduct, as well as histological appearances of other major tissues, remain unaffected in the KO mice, suggesting Iqcg's specific role in spermiogenesis (PMID: 24849454).