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IQGAP1 Monoklonaler Antikörper

IQGAP1 Monoklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

2E11A2

Kat-Nr. : 68588-1-PBS

Synonyme

2E11A2, HUMORFA01, KIAA0051, p195, Ras GTPase-activating-like protein IQGAP1

Filter:
  • Western Blot (WB) analysis of various lysates using IQGAP1 Monoclonal antibody (68588-1-Ig)

    WB analysis using 68588-1-Ig (same clone as 68588-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68588-1-Ig (IQGAP1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68588-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using IQGAP1 Monoclonal antibody (68588-1-Ig)

    IHC staining of human skin cancer using 68588-1-Ig (same clone as 68588-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 68588-1-Ig (IQGAP1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68588-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68588-1-PBS bindet in WB, IHC, ELISA IQGAP1 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen IQGAP1 fusion protein Ag19321
Vollständiger Name IQ motif containing GTPase activating protein 1
Berechnetes Molekulargewicht 189 kDa
Beobachtetes Molekulargewicht 190-195 kDa
GenBank-ZugangsnummerBC151834
Gene symbol IQGAP1
Gene ID (NCBI) 8826
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IQGAP1 is a member of a family of scaffolding proteins that interact with signaling and structural molecules. It localizes to sites of cell-cell contact in epithelial cells and regulates distinct cellular processes including cell adhesion, cell migration, extracellular signals through interacting with numerous protein. Multiple studies have shown that IQGAP1 is up-regulated in many human malignancies, such as lung cancer, ovarian cancer, colon cancer, breast cancer, melanoma and HCC. And IQGAP1 plays a critical role in cancer cell invasion.