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IRF5 Monoklonaler Antikörper

IRF5 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A4A10

Kat-Nr. : 66835-1-PBS

Synonyme

3A4A10, interferon regulatory factor 5, IRF 5, IRF-5 , SLEB10

Filter:
  • Western Blot (WB) analysis of A549 cells using IRF5 Monoclonal antibody (66835-1-Ig)

    WB analysis of A549 using 66835-1-Ig (same clone as 66835-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of THP-1 cells using IRF5 Monoclonal antibody (66835-1-Ig)

    WB analysis of THP-1 using 66835-1-Ig (same clone as 66835-1-PBS)

    THP-1 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of RAW 264.7 cells using IRF5 Monoclonal antibody (66835-1-Ig)

    WB analysis of RAW 264.7 using 66835-1-Ig (same clone as 66835-1-PBS)

    RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using IRF5 Monoclonal antibody (66835-1-Ig)

    WB analysis of HeLa using 66835-1-Ig (same clone as 66835-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 66835-1-Ig (IRF5 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66835-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66835-1-PBS bindet in WB, Indirect ELISA IRF5 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen IRF5 fusion protein Ag5442
Vollständiger Name interferon regulatory factor 5
Berechnetes Molekulargewicht 56 kDa
Beobachtetes Molekulargewicht 56 kDa
GenBank-ZugangsnummerBC004201
Gene symbol IRF5
Gene ID (NCBI) 3663
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.