• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

ISLR2 Polyklonaler Antikörper

ISLR2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24814-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ISLR2 Polyclonal antibody (24814-1-AP)

    WB analysis using 24814-1-AP (same clone as 24814-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24814-1-AP (ISLR2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24814-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24814-1-PBS bindet in WB, Indirect ELISA ISLR2 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ISLR2 fusion protein Ag20518
Vollständiger Name immunoglobulin superfamily containing leucine-rich repeat 2
Berechnetes Molekulargewicht 745 aa, 79 kDa
Beobachtetes Molekulargewicht79 kDa, 130 kDa
GenBank-ZugangsnummerBC152429
Gene symbol ISLR2
Gene ID (NCBI) 57611
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2), also known as LINX. It is expected to be located in cell membrane and the protein is mainly expressed in brain and testis. While the first knockout mouse had impaired development of the internal capsule and no hydrocephalus, a much more recent independent knockout mouse was shown to additionally have severe hydrocephalus. Although the mechanism remains unclear, it may be related to the role of ISLR2 in reorganizing the cytoskeleton of developing neurons (PMID: 30483960). The calculated molecular weight of ISLR2 is 79 kDa, this target has phosphorylation modification and glycosylation modification. And the 130 kDa band is glycosylated (PMID: 29739947).