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ISLR2 Rekombinanter Antikörper

ISLR2 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241227D3

Kat-Nr. : 84076-1-PBS

Synonyme

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  • Cytometric bead array standard curve of MP00978-1

    Cytometric bead array standard curve of MP00978-1

    Cytometric bead array standard curve of MP00978-1, ISLR2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84076-1-PBS. Detection antibody: 84076-2-PBS. Standard: Ag20505. Range: 0.781-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

84076-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA ISLR2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ISLR2 fusion protein Ag20505
Vollständiger Name immunoglobulin superfamily containing leucine-rich repeat 2
Berechnetes Molekulargewicht 745 aa, 79 kDa
GenBank-ZugangsnummerBC152429
Gene symbol ISLR2
Gene ID (NCBI) 57611
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2), also known as LINX. It is expected to be located in cell membrane and the protein is mainly expressed in brain and testis. While the first knockout mouse had impaired development of the internal capsule and no hydrocephalus, a much more recent independent knockout mouse was shown to additionally have severe hydrocephalus. Although the mechanism remains unclear, it may be related to the role of ISLR2 in reorganizing the cytoskeleton of developing neurons (PMID: 30483960). The calculated molecular weight of ISLR2 is 79 kDa, this target has phosphorylation modification and glycosylation modification. And the 130 kDa band is glycosylated (PMID: 29739947).