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ITLN2 Polyklonaler Antikörper

ITLN2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18815-1-PBS

Synonyme

Intelectin-2, intelectin 2, HL2, HL 2, Endothelial lectin HL-2

Filter:
  • Western Blot (WB) analysis of various lysates using ITLN2 Polyclonal antibody (18815-1-AP)

    WB analysis using 18815-1-AP (same clone as 18815-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 18815-1-AP (ITLN2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18815-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon cancer tissue using ITLN2 Polyclonal antibody (18815-1-AP)

    IHC staining of human colon cancer using 18815-1-AP (same clone as 18815-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer slide using 18815-1-AP (ITLN2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18815-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18815-1-PBS bindet in WB, IHC, Indirect ELISA ITLN2 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name intelectin 2
Berechnetes Molekulargewicht 36 kDa
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC143341
Gene symbol ITLN2
Gene ID (NCBI) 142683
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ITLN2 also named as UNQ2789 and PRO7179, may play a role in the defense system against pathogens. Intelectins (intestinal lectins) are highly conserved across chordate evolution and have been implicated in various human diseases, including Crohn's disease (CD). The human genome encodes two intelectin genes, intelectin-1 (ITLN1) and intelectin-2 (ITLN2). It is reproted that human ITLN2 is expressed in Paneth cells, where it localizes to secretory granules, and establish that ITLN2 is a highly abundant multimeric protein secreted into the lumen of the small intestine (PMID: 35182405). The calculated molecular weight of ITLN2 is 36 kDa.