ITM2A Polyklonaler Antikörper

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• KD/KO Validated

ITM2A Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 14407-1-AP

Synonyme

BRICD2A, E25A, integral membrane protein 2A, ITM2A, Protein E25

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  WB analysis of mouse lung using 14407-1-AP

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 14407-1-AP (ITM2A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mauslungengewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IHC: See 1 publications below

Produktinformation

14407-1-AP bindet in WB, IHC, ELISA ITM2A und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ITM2A fusion protein Ag5692
• Vollständiger Name: integral membrane protein 2A
• Berechnetes Molekulargewicht: 30 kDa
• Beobachtetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: BC040437
• Gene symbol: ITM2A
• Gene ID (NCBI): 9452
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Integral membrane protein 2A (ITM2A) is a single-pass type II membrane protein belonging to a family,which is composed of at least two other members ITM2B and ITM2C. ITM2A can be induced during thymocyte selection and T cell activation. In early stages of differentiation ITM2A may be associated with an inhibition of the initiation of chondrogenesis.Catalog#14407-1-AP recognises two band of 30 kDa and 45-48 kDa, and the additional 45-48 kDa band may be due to glycosylation.

Publikationen

Species	Application	Title
	WB	Front Oncol; ITM2A as a Tumor Suppressor and Its Correlation With PD-L1 in Breast Cancer.; Authors - Rui Zhang
mouse	WB	Adipocyte; Itm2a silencing rescues lamin A mediated inhibition of 3T3-L1 adipocyte differentiation.; Authors - Stephanie J Davies ; KD Validated
human	WB,IHC	Front Immunol; Integrating machine learning, bioinformatics and experimental verification to identify a novel prognostic marker associated with tumor immune microenvironment in head and neck squamous carcinoma; Authors - Xiaoxia Zeng