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ITM2B Polyklonaler Antikörper

ITM2B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12193-1-PBS

Synonyme

ABRI, Bri, BRI2, BRI2 intracellular domain, BRI2, membrane form

Filter:
  • Western Blot (WB) analysis of various lysates using ITM2B Polyclonal antibody (12193-1-AP)

    WB analysis using 12193-1-AP (same clone as 12193-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12193-1-AP (ITM2B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12193-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ITM2B Polyclonal antibody (12193-1-AP)

    WB analysis using 12193-1-AP (same clone as 12193-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12193-1-AP (ITM2B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12193-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12193-1-PBS bindet in WB, Indirect ELISA ITM2B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ITM2B fusion protein Ag2831
Vollständiger Name integral membrane protein 2B
Berechnetes Molekulargewicht 266 aa, 30 kDa
Beobachtetes Molekulargewicht 40 kDa
GenBank-ZugangsnummerBC016148
Gene symbol ITM2B
Gene ID (NCBI) 9445
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ITM2B plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. It plays a role in the induction of neurite outgrowth and functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.