ITPR1-Specific Rekombinanter Antikörper

ITPR1-Specific Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242274B10

Kat-Nr. : 85101-1-PBS

Synonyme

ITPR1, 242274B10, ACV, Inositol 1,4,5 trisphosphate receptor, Inositol 1,4,5-trisphosphate receptor type 1

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  WB analysis using 85101-1-RR (same clone as 85101-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85101-1-RR (ITPR1-specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 85101-1-RR (same clone as 85101-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85101-1-RR (ITPR1-Specific antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 85101-1-RR (same clone as 85101-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85101-1-RR (ITPR1-Specific antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85101-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85101-1-PBS bindet in WB, IHC, Indirect ELISA ITPR1-Specific und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: inositol 1,4,5-triphosphate receptor, type 1
• Berechnetes Molekulargewicht: 314 kDa
• Beobachtetes Molekulargewicht: 290-300 kDa
• GenBank-Zugangsnummer: NM_001099952
• Gene symbol: ITPR1
• Gene ID (NCBI): 3708
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ITPR1, also named as INSP3R1 and IP3R, belongs to the InsP3 receptor family. It is a receptor for inositol 1,4,5-trisphosphate which is a second messenger that mediates the release of intracellular calcium. Defects in ITPR1 are the cause of spinocerebellar ataxia type 15 (SCA15). The antibody has no cross reaction with ITPR2 and ITPR3.