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ITPR2 Polyklonaler Antikörper

ITPR2 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20730-1-PBS

Synonyme

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  • Immunohistochemistry (IHC) staining of human small intestine tissue using ITPR2 Polyclonal antibody (20730-1-AP)

    IHC staining of human small intestine using 20730-1-AP (same clone as 20730-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 20730-1-AP (ITPR2 antibody) at dilution of 1:200 (under 10x lens).. This data was developed using the same antibody clone with 20730-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20730-1-PBS bindet in IHC, Indirect ELISA ITPR2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name inositol 1,4,5-triphosphate receptor, type 2
Berechnetes Molekulargewicht 308 kDa
GenBank-ZugangsnummerNM_002223
Gene symbol ITPR2
Gene ID (NCBI) 3709
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production.