ITPR3 Rekombinanter Antikörper

ITPR3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241859B6

Kat-Nr. : 84693-1-PBS

Synonyme

IP3R3, IP3R 3, IP3R, InsP3R3, 241859B6

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  WB analysis using 84693-1-RR (same clone as 84693-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84693-1-RR (ITPR3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84693-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84693-1-PBS bindet in WB, Indirect ELISA ITPR3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: inositol 1,4,5-triphosphate receptor, type 3
• Berechnetes Molekulargewicht: 304 kDa
• Beobachtetes Molekulargewicht: 250-300 kDa
• GenBank-Zugangsnummer: NM_002224
• Gene symbol: ITPR3
• Gene ID (NCBI): 3710
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ITPRs family have three members: ITPR1, ITPR2 and ITPR3. For ITPR3, it is associated with cervical squamous cell carcinoma, glioblastoma, cholangiocarcinoma and other cancers. Inositol 1,4, 5-triphosphate receptor type 3 (ITPR3) was found to be apical-located in bile duct cells, and disruption of lipid raft in the segregated bile duct unit (IBDU) redistributes ITPR3 and impairs Ca2+ waves. (PMID: 35580861, PMID:35852334)