IYD Polyklonaler Antikörper

IYD Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IF, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 16667-1-AP

Synonyme

C6orf71, DEHAL1, Iodotyrosine dehalogenase 1, iodotyrosine deiodinase, IYD, IYD 1

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  WB analysis of human liver using 16667-1-AP

  human liver tissue were subjected to SDS PAGE followed by western blot with 16667-1-AP (IYD antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Lebergewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• IHC: See 1 publications below
• IF: See 1 publications below

Produktinformation

16667-1-AP bindet in WB, IF, IHC, ELISA IYD und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IYD fusion protein Ag10146
• Vollständiger Name: iodotyrosine deiodinase
• Berechnetes Molekulargewicht: 289 aa, 33 kDa
• Beobachtetes Molekulargewicht: 33 kDa
• GenBank-Zugangsnummer: BC056253
• Gene symbol: IYD
• Gene ID (NCBI): 389434
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IYD(Iodotyrosine dehalogenase 1) is also named as C6orf71, DEHAL1 and belongs to the nitroreductase family. It is a transmembrane protein that deiodinates mono-and di-iodotyrosines (MIT, DIT) and recycles iodine, a scarce element in the environment, for the efficient synthesis of thyroid hormone. This protein has 6 isoforms produced by alternative splicing.

Publikationen

Species	Application	Title
human	WB	Toxicology; Structure-activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity.; Authors - Shimizu Ryo R
mouse	IF	Cells; Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart.; Authors - Kyung Ho Han
human	WB	Breast Cancer Res Treat; LncRNA HOTAIR as a ceRNA is related to breast cancer risk and prognosis; Authors - Liyu Qian
mouse	IHC	Cell Tissue Res; The role of vitamin D receptor in predentin mineralization and dental repair after injury; Authors - Yudong Liu