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Importin Beta Rekombinanter Antikörper

Importin Beta Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251633D12

Kat-Nr. : 86630-3-PBS

Synonyme

KPNB1, IMB1, Impnb, Importin 90, Importin subunit beta 1

Filter:
  • Western Blot (WB) analysis of various lysates using Importin Beta Recombinant monoclonal antibody (86630-3-RR)

    WB analysis using 86630-3-RR (same clone as 86630-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86630-3-RR (KPNB1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86630-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86630-3-RR

    Affinity and Kinetic Characterization of 86630-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86630-3-RR against Human Importin Beta were performed. The affinity constant is 1.02 nM.

Geprüfte Anwendungen

Produktinformation

86630-3-PBS bindet in WB, Indirect ELISA Importin Beta und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Importin Beta fusion protein Ag0122
Vollständiger Name karyopherin (importin) beta 1
Berechnetes Molekulargewicht 97 kDa
Beobachtetes Molekulargewicht 90-97 kDa
GenBank-ZugangsnummerBC003572
Gene symbol KPNB1
Gene ID (NCBI) 3837
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Importin beta1, also known karyopherin beta or KPNB1, is a nuclear transport receptor that plays a key role in the nuclear import process. Importin beta1 and importin alpha work in concert to transport cargo into the nucleus, functioning as an essential component of the classical nuclear localization signal (NLS) pathway. Elevated expression of importin beta1 has been found in cervical tumors. (22125623)