Integrin Alpha 4 Monoklonaler Antikörper
Integrin Alpha 4 Monoklonal Antikörper für WB, ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
WB, ELISA
Konjugation
Unkonjugiert
CloneNo.
1B6A3
Kat-Nr. : 67040-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
67040-1-PBS bindet in WB, ELISA Integrin Alpha 4 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG2a |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Integrin Alpha 4 fusion protein Ag28024 |
| Vollständiger Name | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| Berechnetes Molekulargewicht | 1032 aa, 115 kDa |
| Beobachtetes Molekulargewicht | 130-150 kDa |
| GenBank-Zugangsnummer | BC156712 |
| Gene symbol | Integrin alpha 4 |
| Gene ID (NCBI) | 3676 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.







