• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Integrin alpha 11 Rekombinanter Antikörper

Integrin alpha 11 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241351B7

Kat-Nr. : 84695-1-PBS

Synonyme

ITGA11, Integrin alpha-11, 241351B7

Filter:
  • Western Blot (WB) analysis of various lysates using Integrin alpha 11 Recombinant antibody (84695-1-RR)

    WB analysis using 84695-1-RR (same clone as 84695-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84695-1-RR (Integrin alpha 11 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84695-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84695-1-PBS bindet in WB, Indirect ELISA Integrin alpha 11 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name integrin, alpha 11
Berechnetes Molekulargewicht 133 kDa
Beobachtetes Molekulargewicht170 kDa
GenBank-ZugangsnummerNM_001004439
Gene symbol ITGA11
Gene ID (NCBI) 22801
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID:19118207). Integrin alpha 11 (ITGA11) combines with the beta 1 subunit (ITGB1, CD29) to form a cell-surface receptor for collagen. This receptor is involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells (PMID: 11518510). It is also involved in the regulation of myofibroblast phenotypic differentiation during fibrotic diseases (PMID: 29147013).