JAK3 Rekombinanter Antikörper

JAK3 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3N1

Kat-Nr. : 80331-1-PBS

Synonyme

3N1, EC:2.7.10.2, JAK 3, JAK-3, JAKL

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  WB analysis using 80331-1-RR (same clone as 80331-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 80331-1-RR (JAK3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 80331-1-RR (JAK3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 80331-1-RR (same clone as 80331-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 80331-1-RR (JAK3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 80331-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

80331-1-PBS bindet in WB, IHC, Indirect ELISA JAK3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: Janus kinase 3 (a protein tyrosine kinase, leukocyte)
• Berechnetes Molekulargewicht: 1124 aa, 125 kDa
• Beobachtetes Molekulargewicht: 125 kDa
• GenBank-Zugangsnummer: BC028068
• Gene symbol: JAK3
• Gene ID (NCBI): 3718
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

JAK3 is a non-receptor tyrosine kinase, predominantly expressed in hematopoietic cells and that has been implicated in the signal transduction of the common gamma chain subfamily of cytokine receptors. As a result, JAK3 plays an essential role in hematopoieisis during T cell development. JAK3 belongs to the Janus kinase family of receptor-associated tyrosine kinases located in cytoplasm adjacent to the plasma membrane. (PMID: 19747563, PMID: 33767339)