JAM-A/CD321 Rekombinanter Antikörper

JAM-A/CD321 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250060G10

Kat-Nr. : 98516-2-PBS

Synonyme

CD321, F11r, Jam1, JAM-1, JAM-A

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  FC experiment of mouse peripheral blood platelets using 98516-2-RR (same clone as 98516-2-PBS)

  1x10^6 mouse peripheral blood platelets were surface stained with 0.25 ug Anti-Mouse JAM-A/CD321 Rabbit RecAb (98516-2-RR, Clone: 250060G10) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red). Cells were not fixed. This data was developed using the same antibody clone with 98516-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98516-2-PBS bindet in FC JAM-A/CD321 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: JAM-A/CD321 fusion protein Eg3117
• Vollständiger Name: F11 receptor
• Berechnetes Molekulargewicht: 32 kDa
• GenBank-Zugangsnummer: NM_172647.2
• Gene symbol: F11r
• Gene ID (NCBI): 16456
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Junctional adhesion molecule A (JAM-A), also known as CD321 or F11 receptor (F11R), is a transmembrane protein that belongs to the immunoglobulin superfamily of cell adhesion molecules. JAM-A is present in epithelial cells, endothelial cells, leukocytes, and blood platelets. JAM-A participates in regulating various biological processes, as diverse as paracellular permeability, tight junction formation and maintenance, leukocyte transendothelial migration, epithelial-to-mesenchymal transition, angiogenesis, reovirus binding, and platelet activation.