JNK Rekombinanter Antikörper
JNK Rekombinant Antikörper für WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
6J16
Kat-Nr. : 81629-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
81629-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA JNK und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | JNK fusion protein Ag1639 |
Vollständiger Name | mitogen-activated protein kinase 8 |
Berechnetes Molekulargewicht | 48 kDa |
Beobachtetes Molekulargewicht | 44-48 kDa, 50-55 kDa |
GenBank-Zugangsnummer | BC130572 |
Gene symbol | JNK |
Gene ID (NCBI) | 5599 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has some isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot(PMID:11062067 ). This antibody can recognize JNK1, JNK2 and JNK3.