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Jagged1/CD339 Monoklonaler Antikörper

Jagged1/CD339 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgA

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

2A7D11

Kat-Nr. : 66890-1-PBS

Synonyme

JAG1, Jagged1, 2A7D11, CD339, HJ1

Filter:
  • Western Blot (WB) analysis of HEK-293 cells using Jagged1/CD339 Monoclonal antibody (66890-1-Ig)

    WB analysis of HEK-293 using 66890-1-Ig (same clone as 66890-1-PBS)

    WB result of Jagged1 antibody (66890-1-Ig; 1:12000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Jagged1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66890-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HT-29 cells using Jagged1/CD339 Monoclonal antibody (66890-1-Ig)

    WB analysis of HT-29 using 66890-1-Ig (same clone as 66890-1-PBS)

    HT-29 cells were subjected to SDS PAGE followed by western blot with 66890-1-Ig (Jagged1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66890-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66890-1-PBS bindet in WB, ELISA Jagged1/CD339 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgA
Klonalität Monoklonal
Typ Antikörper
Immunogen Jagged1/CD339 fusion protein Ag11891
Vollständiger Name jagged 1 (Alagille syndrome)
Berechnetes Molekulargewicht 1218 aa, 134 kDa
Beobachtetes Molekulargewicht 150 kDa
GenBank-ZugangsnummerBC098393
Gene symbol Jagged1
Gene ID (NCBI) 182
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Thiophiler Affinitätschromatograph
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Jagged1 is a type I, membrane- anchored, multidomain protein and a ligand of the Notch receptor. The receptor-ligand interaction can trigger the Notch signaling and activate transcription factors that play key roles in cell differentiation and morphogenesis. The predicted MW of Jagged1 is 134 kDa, while higher MW around 150-180 kDa had been observed in literations (PMID: 9716576, 9596653).