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KCNA1 Polyklonaler Antikörper

KCNA1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18067-1-PBS

Synonyme

AEMK, EA1, HBK1, HUK1, KV1.1

Filter:
  • Western Blot (WB) analysis of various lysates using KCNA1 Polyclonal antibody (18067-1-AP)

    WB analysis using 18067-1-AP (same clone as 18067-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 18067-1-AP (KCNA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18067-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18067-1-PBS bindet in WB, Indirect ELISA KCNA1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KCNA1 fusion protein Ag12699
Vollständiger Name potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Berechnetes Molekulargewicht 495 aa, 56 kDa
Beobachtetes Molekulargewicht86 kDa
GenBank-ZugangsnummerBC101733
Gene symbol KCNA1
Gene ID (NCBI) 3736
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Potassium voltage-gated channel subfamily A member 1 (KCNA1, also known as Kv1.1) is a voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney (PMID: 19903818; 8845167). KCNA1 expression was reduced in human cancers, and this decrease correlated with an increase in breast cancer aggressiveness (PMID: 23774215). Furthermore, Kv1.1 is expressed in the brain as a mature glycoprotein, which is reported to be 86 kDa (PMID: 16305740).