• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

KCNA3 Rekombinanter Antikörper

KCNA3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242588H8

Kat-Nr. : 85049-4-PBS

Synonyme

Kv1.3, HUKIII, HPCN3, HLK3, HGK5

Filter:
  • Western Blot (WB) analysis of U-937 cells using KCNA3 Recombinant antibody (85049-4-RR)

    WB analysis of U-937 using 85049-4-RR (same clone as 85049-4-PBS)

    U-937 cells were subjected to SDS PAGE followed by western blot with 85049-4-RR (KCNA3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85049-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85049-4-RR

    Affinity and Kinetic Characterization of 85049-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85049-4-RR against Human KCNA3 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85049-4-PBS bindet in WB, Indirect ELISA KCNA3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen KCNA3 fusion protein Ag5204
Vollständiger Name potassium voltage-gated channel, shaker-related subfamily, member 3
Berechnetes Molekulargewicht 575 aa, 64 kDa
Beobachtetes Molekulargewicht75 kDa
GenBank-ZugangsnummerBC035059
Gene symbol KCNA3
Gene ID (NCBI) 3738
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Kv1.3 ( also known as KCNA3, MK3, HGK5, HLK3, PCN3, HPCN3) contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, which allows nerve cells to repolarize following an action potential efficiently. It plays an essential role in T cell proliferation and activation. Kv1.3 channels are expressed in various tissues and cell types including the brain, vascular smooth muscle cells, and leucocytes. Malfunction of Kv1.3 can alter the immune response, elicit neurotoxic effects or impact on cancer growth(PMID: 24305723; 24133455).