Kv1.4-Specific Polyklonaler Antikörper

Kv1.4-Specific Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 19697-1-AP

Synonyme

KCNA4, KV1.4, HBK4, HK1, HPCN2

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  WB analysis using 19697-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 19697-1-AP (Kv1.4-Specific antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mauslebergewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 3 publications below

Produktinformation

19697-1-AP bindet in WB, ELISA Kv1.4-Specific und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: potassium voltage-gated channel, shaker-related subfamily, member 4
• Berechnetes Molekulargewicht: 73 kDa
• Beobachtetes Molekulargewicht: 68-73 kDa
• GenBank-Zugangsnummer: NM_002233
• Gene symbol: Kv1.4
• Gene ID (NCBI): 3739
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KCNA4, also named as KCNA4L, HBK4, HUKII, HK1 and HPCN2, belongs to the potassium channel family and A (Shaker) subfamily. KCN4 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The antibody is specific to KCN4.

Publikationen

Species	Application	Title
rat	WB	Cell Physiol Biochem; MiR-223-3p as a Novel MicroRNA Regulator of Expression of Voltage-Gated K+ Channel Kv4.2 in Acute Myocardial Infarction.; Authors - Xue Liu
rat	WB	J Cell Sci; Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity.; Authors - Xueting Gao
rat	WB	J Cell Mol Med; Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity.; Authors - Yi Guan