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KCNE2 Polyklonaler Antikörper

KCNE2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17920-1-PBS

Synonyme

MinK-related peptide 1, MinK related peptide 1, Minimum potassium ion channel-related peptide 1, LQT6, LQT5

Filter:
  • Western Blot (WB) analysis of various lysates using KCNE2 Polyclonal antibody (17920-1-AP)

    WB analysis using 17920-1-AP (same clone as 17920-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17920-1-AP (KCNE2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17920-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17920-1-PBS bindet in WB, Indirect ELISA KCNE2 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KCNE2 fusion protein Ag12336
Vollständiger Name potassium voltage-gated channel, Isk-related family, member 2
Berechnetes Molekulargewicht 123 aa, 14 kDa
Beobachtetes Molekulargewicht30 kDa
GenBank-ZugangsnummerBC093892
Gene symbol KCNE2
Gene ID (NCBI) 9992
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Potassium voltage-gated channel subfamily E regulatory subunit 2 (KCNE2, also known as LQT5, LQT6, ATFB4, and MIRP1) functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits (PMID: 10219239; 11034315; 11101505; 12185453; 20533308). KCNE2 beta subunit modulates the gating kinetics and enhances the stability of the channel complex (PMID: 10219239; 11034315; 11101505; 12185453; 20533308). It is expressed in various parts of the heart, with higher levels observed in the ventricles and Purkinje tissues compared to the atria (PMID: 39272981). KCNE2 has three forms, such as the core (15 kDa), singly glycosylated (20 kDa), and doubly glycosylated (25 kDa) forms (PMID: 15066947).