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KCNQ5 Polyklonaler Antikörper

KCNQ5 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28000-1-PBS

Synonyme

Voltage-gated potassium channel subunit Kv7.5, Potassium voltage-gated channel subfamily KQT member 5, Kv7.5, KQT-like 5, KQT like 5

Filter:
  • Western Blot (WB) analysis of various lysates using KCNQ5 Polyclonal antibody (28000-1-AP)

    WB analysis using 28000-1-AP (same clone as 28000-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28000-1-AP (KCNQ5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28000-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of Raji cells using KCNQ5 Polyclonal antibody (28000-1-AP)

    IP experiment of Raji using 28000-1-AP (same clone as 28000-1-PBS)

    IP result of anti-KCNQ5 (IP:28000-1-AP, 4ug; Detection:28000-1-AP 1:500) with Raji cells lysate 1600 ug. This data was developed using the same antibody clone with 28000-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28000-1-PBS bindet in WB, IP, Indirect ELISA KCNQ5 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KCNQ5 fusion protein Ag27622
Vollständiger Name potassium voltage-gated channel, KQT-like subfamily, member 5
Berechnetes Molekulargewicht 102 kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerNM_001160130
Gene symbol KCNQ5
Gene ID (NCBI) 56479
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Potassium voltage-gated channel subfamily Q member 5 (KCNQ5, also known as Kv7.5 and MRD46) is widely expressed in the brain and generates M-type current. It has a role in the regulation of neuronal excitability (PMID: 10816588). KCNQ5 mutations are associated with increased excitability and decreased repolarization reserve, lead to pathophysiology (PMID: 28669405).