KCNV1 Rekombinanter Antikörper

KCNV1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

242865E3

Kat-Nr. : 85153-3-RR

Synonyme

242865E3, HNKA, KCNB3, KV2.3, KV8.1

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  WB analysis using 85153-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85153-3-RR (KCNV1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 85153-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85153-3-RR (KCNV1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  IHC staining of mouse brain using 85153-3-RR

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85153-3-RR (KCNV1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of rat brain using 85153-3-RR

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85153-3-RR (KCNV1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  Affinity and Kinetic Characterization of 85153-3-RR

  Biolayer interferometry (BLl) kinetic assays of 85153-3-RR against Human KCNV1 were performed. The affinity constant is 0.70 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, C6-Zellen, fetales humanes Hirngewebe, Rattenhirngewebe, U-87 MG-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

85153-3-RR bindet in WB, ELISA KCNV1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: KCNV1 fusion protein Ag3376
• Vollständiger Name: potassium channel, subfamily V, member 1
• Berechnetes Molekulargewicht: 500 aa, 56 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC028739
• Gene symbol: KCNV1
• Gene ID (NCBI): 27012
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Potassium voltage-gated channel subfamily V member 1 (KCNV1, also known as Kv8.1) is a voltage-gated potassium channel that plays a role in the repolarization phase of the action potential (PMID: 39003683). It is involved in regulating neuronal excitability and is essential for maintaining normal electrical signaling in the nervous system (PMID: 38911266). The function of KCNV1 may also include inhibiting specific types of outwardly rectifying potassium channels (PMID: 8670833).