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KDM5C Polyklonaler Antikörper

KDM5C Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14426-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using KDM5C Polyclonal antibody (14426-1-AP)

    WB analysis using 14426-1-AP (same clone as 14426-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14426-1-AP (KDM5C antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14426-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using KDM5C Polyclonal antibody (14426-1-AP)

    IF Staining of HeLa using 14426-1-AP (same clone as 14426-1-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed HeLa cells using 14426-1-AP (KDM5C antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14426-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14426-1-PBS bindet in WB, IF/ICC, Indirect ELISA KDM5C und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KDM5C fusion protein Ag5791
Vollständiger Name lysine (K)-specific demethylase 5C
Berechnetes Molekulargewicht 176 kDa
Beobachtetes Molekulargewicht 171-180 kDa
GenBank-ZugangsnummerBC054499
Gene symbol KDM5C
Gene ID (NCBI) 8242
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KDM5C belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell differentiation (PMID:21575681). KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues (PMID:17320160,17320161).