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KDM5C Rekombinanter Antikörper

KDM5C Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250484C10

Kat-Nr. : 86017-1-PBS

Synonyme

[histone H3]-trimethyl-L-lysine(4) demethylase 5C, DXS1272E, EC:1.14.11.67, JARID1C, Jumonji/ARID domain-containing protein 1C

Filter:
  • Western Blot (WB) analysis of various lysates using KDM5C Recombinant antibody (86017-1-RR)

    WB analysis using 86017-1-RR (same clone as 86017-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86017-1-RR (KDM5C antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86017-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86017-1-RR

    Affinity and Kinetic Characterization of 86017-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86017-1-RR against Human KDM5C were performed. The affinity constant is 0.148 nM.

Geprüfte Anwendungen

Produktinformation

86017-1-PBS bindet in WB, Indirect ELISA KDM5C und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen KDM5C fusion protein Ag5791
Vollständiger Name lysine (K)-specific demethylase 5C
Berechnetes Molekulargewicht 176 kDa
Beobachtetes Molekulargewicht171-180 kDa
GenBank-ZugangsnummerBC054499
Gene symbol KDM5C
Gene ID (NCBI) 8242
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KDM5C belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell differentiation (PMID:21575681). KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues (PMID:17320160,17320161).