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KIAA0196 Polyklonaler Antikörper

KIAA0196 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32028-1-PBS

Synonyme

WASHC5, WASH complex subunit strumpellin, WASH complex subunit 5, Strumpellin

Filter:
  • Western Blot (WB) analysis of various lysates using KIAA0196 Polyclonal antibody (32028-1-AP)

    WB analysis using 32028-1-AP (same clone as 32028-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32028-1-AP (KIAA0196 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32028-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32028-1-PBS bindet in WB, Indirect ELISA KIAA0196 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KIAA0196 fusion protein Ag36916
Vollständiger Name KIAA0196
Berechnetes Molekulargewicht134kDa，1159aa
Beobachtetes Molekulargewicht120 kDa
GenBank-ZugangsnummerNM_014846.3
Gene symbol KIAA0196
Gene ID (NCBI) 9897
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIAA0196 is a core component of the WASH complex, an actin-regulating complex involved in intracellular trafficking, mitochondrial metabolism, and myelination. It plays a crucial role in maintaining the structural integrity of myofibrils and regulating cardiac function. Recent studies have identified KIAA0196 as a susceptibility gene for abnormal cardiac development. Mutations or reduced expression of KIAA0196 can lead to cardiac defects, such as enlarged hearts and myocardial contractile dysfunction (PMID: 32417190).