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KIAA0319L Monoklonaler Antikörper

KIAA0319L Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2E11D9

Kat-Nr. : 68717-1-PBS

Synonyme

KIAA0319 like, KIAA0319L, KIAA1837, PKD1 like, PP791, RP4 765A10.3

Filter:
  • Western Blot (WB) analysis of various lysates using KIAA0319L Monoclonal antibody (68717-1-Ig)

    WB analysis using 68717-1-Ig (same clone as 68717-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68717-1-Ig (KIAA0319L antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68717-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68717-1-PBS bindet in WB, Indirect ELISA KIAA0319L und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen KIAA0319L fusion protein Ag15263
Vollständiger Name KIAA0319-like
Berechnetes Molekulargewicht 1049 aa, 116 kDa
Beobachtetes Molekulargewicht140-150 kDa
GenBank-ZugangsnummerBC031672
Gene symbol KIAA0319L
Gene ID (NCBI) 79932
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIAA0319L (also known as AAVR) is a type-I transmembrane protein that acts as a receptor for adeno-associated virus (AAV) and is involved in adeno-associated virus infection through endocytosis system (PMID: 26814968). It has been shown that KIAA0319L is highly-glycosylated and can localise to the plasma membrane, endosomes, Golgi and trans-Golgi network (TGN) (PMID: 29991750). KIAA0319L gene has been associated with susceptibility to developmental dyslexia or reading disabilities (PMID: 19085271). The predicted molecular mass of KIAA0319L is 116 kDa, but western blot detected protein at 150 kDa in lysate from HeLa cells, likely due to glycosidic linkages (PMID: 28679762; 30962536).