CEP104 Polyklonaler Antikörper

CEP104 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31847-1-PBS

Synonyme

KIAA0562, Centrosomal protein of 104 kDa, Centrosomal Protein 104kDa, Centrosomal Protein 104

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  WB analysis using 31847-1-AP (same clone as 31847-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31847-1-AP (KIAA0562 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31847-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31847-1-PBS bindet in WB, Indirect ELISA CEP104 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CEP104 fusion protein Ag35662
• Vollständiger Name: KIAA0562
• Berechnetes Molekulargewicht: 104kDa，925aa
• Beobachtetes Molekulargewicht: 70 kDa
• GenBank-Zugangsnummer: NM_014704.3
• Gene symbol: KIAA0562
• Gene ID (NCBI): 9731
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIAA0562, also known as CEP104 (centrosomal protein 104), is a gene encoding a centrosomal protein that is essential for ciliogenesis and the structural integrity of the cilium tip. During ciliogenesis, CEP104 is translocated from the distal tip of the centriole to the elongated cilium tip. CEP104 is expressed in a variety of cell types, including tissues such as testis and kidney. Mutations in its gene are associated with the autosomal recessive disorder Joubert syndrome, which is characterized by distinctive mid-hindbrain and cerebellar malformations, actinic dyskinesia, irregular breathing, developmental delay, and ataxia. In studies, inhibitors of CEP104 such as Cytochalasin D and Vismodegib have been used to investigate their specific role in cellular function.