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RIC1 Polyklonaler Antikörper

RIC1 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32377-1-PBS

Synonyme

CIP150, KIAA1432, Protein RIC1 homolog, Q4ADV7

Filter:
  • Western Blot (WB) analysis of various lysates using RIC1 Polyclonal antibody (32377-1-AP)

    WB analysis using 32377-1-AP (same clone as 32377-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32377-1-AP (KIAA1432 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32377-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HeLa cells using RIC1 Polyclonal antibody (32377-1-AP)

    IP experiment of HeLa using 32377-1-AP (same clone as 32377-1-PBS)

    IP result of anti-RIC1 (IP:32377-1-AP, 4ug; Detection:32377-1-AP 1:1000) with HeLa cells lysate 1880 ug. This data was developed using the same antibody clone with 32377-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32377-1-PBS bindet in WB, IP, Indirect ELISA RIC1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RIC1 fusion protein Ag36426
Vollständiger Name KIAA1432
Beobachtetes Molekulargewicht150 kDa
GenBank-ZugangsnummerBC136616
Gene symbol KIAA1432
Gene ID (NCBI) 57589
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RIC1 (RAB6A GEF complex partner 1) is a protein that plays a critical role in intracellular membrane trafficking. It encodes a protein of 1056 amino acid (aa) residues, including a putative nuclear localisation sequence (PMID: 9099877). Ric1 is composed of two β-propellers and a C-terminal α-solenoid domain that remodels the Rab6 nucleotide-binding pocket to facilitate nucleotide exchange (PMID: 39632878). RIC1 proteins play important roles in vesicular trafficking, regulation of membrane dynamics, cell division and signalling, and are essential for maintaining normal cellular function.