KIAA2013 Monoklonaler Antikörper

KIAA2013 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4G6C4

Kat-Nr. : 68245-1-PBS

Synonyme

4G6C4

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  WB analysis using 68245-1-Ig (same clone as 68245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68245-1-Ig (KIAA2013 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68245-1-Ig (same clone as 68245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68245-1-Ig (KIAA2013 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 68245-1-Ig (same clone as 68245-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using KIAA2013 antibody (68245-1-Ig, Clone: 4G6C4 ) at dilution of 1:1000 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68245-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68245-1-PBS bindet in WB, IF/ICC, Indirect ELISA KIAA2013 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: KIAA2013 fusion protein Ag27438
• Vollständiger Name: KIAA2013
• Beobachtetes Molekulargewicht: 65 kDa
• GenBank-Zugangsnummer: BC035033
• Gene symbol: KIAA2013
• Gene ID (NCBI): 90231
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIAA2013, also known as Q8IYS2 or MGC33867, is a single-pass transmembrane protein encoded by the KIAA2013 gene in humans. KIAA2013 has been found to play a role in the Endocannabinoid system. This system is made up of cannabinoid receptors 1 and 2 (CB1 and CB2) as well as the various ligands and enzymes that interact. The protein KIAA2013 has been found to be expressed within CB2 expressing cells. Both cannabinoid receptors are labeled as class A G-Protein Coupled Receptors, and CB2 is highly expressed within the human spleen and leukocytes. CB2, and by extension KIAA2013, are therefore targets of interest for therapeutic studies looking into diseases such as inflammatory bowel disease and rheumatoid arthritis(PMID:31616248 34752341).