KIDINS220 Monoklonaler Antikörper
KIDINS220 Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
3G2D8
Kat-Nr. : 66748-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66748-1-PBS bindet in WB, Indirect ELISA KIDINS220 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2b |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | KIDINS220 fusion protein Ag17624 |
Vollständiger Name | kinase D-interacting substrate, 220kDa |
Berechnetes Molekulargewicht | 1672 aa, 187 kDa |
Beobachtetes Molekulargewicht | 200 kDa |
GenBank-Zugangsnummer | BC130610 |
Gene symbol | KIDINS220 |
Gene ID (NCBI) | 57498 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Kidins220 (Kinase D-interacting substrate 220 kD) is a crucial mediator of signal transduction in neural tissues. Also it named ARMS(Ankyrin Repeat-Rich Membrane Spanning) due to the presence of ankyrin repeats and transmembrane domains together with other binding motifs. It is a multidomain transmembrane protein that not only transduces signaling mediated by the receptor tyrosine kinase (RTK), but also regulates the stability of cytoskeletal network through a number of cytoskeleton-associated proteins, including Septin5, MAPs , and stathmin family members. KIDINS220 exists some isoforms with MV 194 kDa, 185 kDa, 115 kDa, and 60 kDa.