KIF7 Polyklonaler Antikörper

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• KD/KO Validated

KIF7 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24693-1-PBS

Synonyme

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  WB analysis of HEK-293 using 24693-1-AP (same clone as 24693-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 24693-1-AP (KIF7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 24693-1-AP (same clone as 24693-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24693-1-AP (KIF7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HEK-293 using 24693-1-AP (same clone as 24693-1-PBS)

  IP result of anti-KIF7 (IP:24693-1-AP, 5ug; Detection:24693-1-AP 1:500) with HEK-293 cells lysate 1760ug. This data was developed using the same antibody clone with 24693-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24693-1-PBS bindet in WB, IP, Indirect ELISA KIF7 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: KIF7 fusion protein Ag19119
• Vollständiger Name: kinesin family member 7
• Berechnetes Molekulargewicht: 1343 aa, 151 kDa
• Beobachtetes Molekulargewicht: 140 kDa
• GenBank-Zugangsnummer: BC112271
• Gene symbol: KIF7
• Gene ID (NCBI): 374654
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIF7(Kinesin family member 7) is a microtubule interacting protein that functions to regulate Hh signaling by maintaining the architecture of the primary cilium, a complex microtubule-based organelle with many signal transduction functions (PMID: 26439735). KIF7 has been shown to have both negative and positive roles in Shh signal transduction. Without a ligand, KIF7 localizes to the cilium base where it forms a complex with Gli proteins and other pathway components and promotes the processing of GliRs (PMID: 21552264).