KIR2DL2 Polyklonaler Antikörper

KIR2DL2 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31930-1-AP

Synonyme

NKAT-6, NKAT6, Natural killer-associated transcript 6, Killer cell immunoglobulin-like receptor 2DL2, CD158b1

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  WB analysis using 31930-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31930-1-AP (KIR2DL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HuT 78 cells

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

31930-1-AP bindet in WB, ELISA KIR2DL2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: KIR2DL2 fusion protein Ag35284
• Vollständiger Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
• Berechnetes Molekulargewicht: 38 kDa
• Beobachtetes Molekulargewicht: 60,30 kDa
• GenBank-Zugangsnummer: NM_014219
• Gene symbol: KIR2DL2
• Gene ID (NCBI): 3803
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KIR2DL2 is one of killer cell immunoglobulin-like receptors, which are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.