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KIR2DL4/CD158d Polyklonaler Antikörper

KIR2DL4/CD158d Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32059-1-PBS

Synonyme

KIR2DL4, KIR103, KIR 103AS, Killer cell immunoglobulin-like receptor 2DL4, G9P

Filter:
  • Western Blot (WB) analysis of various lysates using KIR2DL4/CD158d Polyclonal antibody (32059-1-AP)

    WB analysis using 32059-1-AP (same clone as 32059-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32059-1-AP (KIR2DL4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32059-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32059-1-PBS bindet in WB, Indirect ELISA KIR2DL4/CD158d und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
Berechnetes Molekulargewicht 377 aa, 42 kDa
Beobachtetes Molekulargewicht45 kDa
GenBank-ZugangsnummerBC041611
Gene symbol KIR2DL4
Gene ID (NCBI) 3805
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells that regulate their responsiveness to signals received from their environment (PMID: 22934097). Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4, also known as CD158D and KIR103AS) is an unusual member of the KIRs family, which activates the cytotoxicity of NK cells. KIR2DL4 has two immunoglobulin domains and a single immunoreceptor tyrosine-based inhibition motif (ITIM) in the cytoplasmic tail with weak inhibitory potential (PMID: 12055234).