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KIR3DL1/CD158E Polyklonaler Antikörper

KIR3DL1/CD158E Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13335-1-PBS

Synonyme

KIR3DL1, CD158 antigen-like family member E, CD158E, CD158E1, HLA-BW4-specific inhibitory NK cell receptor

Filter:
  • Western Blot (WB) analysis of various lysates using KIR3DL1/CD158E Polyclonal antibody (13335-1-AP)

    WB analysis using 13335-1-AP (same clone as 13335-1-PBS)

    human peripheral blood leukocytes were subjected to SDS PAGE followed by western blot with 13335-1-AP (KIR3DL1/CD158E antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13335-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13335-1-PBS bindet in WB, Indirect ELISA KIR3DL1/CD158E und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KIR3DL1/CD158E fusion protein Ag4152
Vollständiger Name killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
Berechnetes Molekulargewicht 444 aa, 49 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC028206
Gene symbol KIR3DL1
Gene ID (NCBI) 3811
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. This antibody is raised against 22-344 amino acids of human KIR3DL1 and recognizes both KIR3DL1 (49 kDa) and KIR3DS1 (43 kDa).