KIR3DL1/CD158E Rekombinanter Antikörper

KIR3DL1/CD158E Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

243022H8

Kat-Nr. : 98389-1-RR

Synonyme

KIR3DL1, CD158 antigen-like family member E, CD158E, CD158E1, HLA-BW4-specific inhibitory NK cell receptor

---

• 

  FC experiment of human PBMCs using 98389-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Human NCAM1/CD56. Cells were not fixed. Lymphocyte were gated.

• 

  FC experiment of human PBMCs using 98389-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human KIR3DL1/CD158E Rabbit RecAb (98389-1-RR, Clone:243022H8)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocyte were gated.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98389-1-RR bindet in FC KIR3DL1/CD158E und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
• Berechnetes Molekulargewicht: 49 kDa
• GenBank-Zugangsnummer: NM_013289.4
• Gene symbol: KIR3DL1
• Gene ID (NCBI): 3811
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous.