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KLF2 Polyklonaler Antikörper

KLF2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23384-1-PBS

Synonyme

Krueppel like factor 2, Krueppel-like factor 2, Kruppel like factor 2 (lung), LKLF, Lung krueppel like factor

Filter:
  • Western Blot (WB) analysis of various lysates using KLF2 Polyclonal antibody (23384-1-AP)

    WB analysis using 23384-1-AP (same clone as 23384-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23384-1-AP (KLF2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23384-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23384-1-PBS bindet in WB, Indirect ELISA KLF2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KLF2 fusion protein Ag20019
Vollständiger Name Kruppel-like factor 2 (lung)
Berechnetes Molekulargewicht 355 aa, 37 kDa
Beobachtetes Molekulargewicht37-40 kDa, 60 kDa
GenBank-ZugangsnummerBC071983
Gene symbol KLF2
Gene ID (NCBI) 10365
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KLF2 (Kruppel-like Factor 2) belongs to zinc finger transcription factors, and it is implicated in a variety of biochemical processes, including lung development, embryonic erythropoiesis, epithelial integrity, T-cell viability, and adipogenesis (PMID: 17904406). KLF2 was identified as a negative regulator of T cell activation and adipogenesis. KLF2 also acts as a novel regulator of endothelial proinflammatory activation, inhibiting the inflammatory cytokine-mediated induction of adhesion molecule expression and immune cell adhesion (PMID:15718498). KLF2-null mice exhibit abnormal blood vessel formation, resulting in embryonic haemorrhage and death (PMID: 32132543). KLF2 can be detected 60 kDa by post-translationally modified (PMID: 36466816).