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KLF6 Monoklonaler Antikörper

KLF6 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

2F8B3

Kat-Nr. : 67297-1-PBS

Synonyme

BCD1, B-cell-derived protein 1, COPEB, Core promoter element-binding protein, CPBP

Filter:
  • Western Blot (WB) analysis of various lysates using KLF6 Monoclonal antibody (67297-1-Ig)

    WB analysis using 67297-1-Ig (same clone as 67297-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67297-1-Ig (KLF6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67297-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67297-1-PBS bindet in WB, ELISA KLF6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen KLF6 fusion protein Ag6859
Vollständiger Name Kruppel-like factor 6
Berechnetes Molekulargewicht 32 kDa
Beobachtetes Molekulargewicht 32-42 kDa
GenBank-ZugangsnummerBC000311
Gene symbol KLF6
Gene ID (NCBI) 1316
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KLF6(krupple-like factor 6) is a zinc finger transcription factor and tumor suppressor with biological activities and transcriptional targets in growing range. It is highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. One key target gene of KLF6 in endoglin, which is a homodimeric cell membrane glycoprotein and TGF-β auxiliary receptor, owns a pro-angiogenic role in endothelial cells and is also involved in malignant progression. Also KLF6 induces apoptosis in prostate cancer cells through upregulation of ATF3. KLF6 was normal detected as a 46kDa protein, which is larger than translation product(32kDa), because of post-translational modification including both phosphorylation and glycosylation. This antibody raise against the full length of KLF6 gene of human origin, and can recognize both of KLF6, included KLF6(~32kDa), p-KLF6(~35-46kDa). Otherwise, there may be a non-specific band(50kDa) showed in detection