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KLHL7 Polyklonaler Antikörper

KLHL7 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32697-1-PBS

Synonyme

Kelch-like protein 7

Filter:
  • Western Blot (WB) analysis of various lysates using KLHL7 Polyclonal antibody (32697-1-AP)

    WB analysis using 32697-1-AP (same clone as 32697-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32697-1-AP (KLHL7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32697-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using KLHL7 Polyclonal antibody (32697-1-AP)

    WB analysis using 32697-1-AP (same clone as 32697-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32697-1-AP (KLHL7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32697-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32697-1-PBS bindet in WB, Indirect ELISA KLHL7 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KLHL7 fusion protein Ag38050
Vollständiger Name kelch-like 7 (Drosophila)
Berechnetes Molekulargewicht 586 aa, 66 kDa
Beobachtetes Molekulargewicht65 kDa
GenBank-ZugangsnummerBC039585
Gene symbol KLHL7
Gene ID (NCBI) 55975
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KLHL7 (Kelch-like protein 7) is a member of the Kelch-like protein family and plays significant roles in various biological processes, including cell cycle regulation, protein degradation, and cytoskeleton organization. KLHL7 is highly expressed in various cancers and is associated with malignant progression and poor prognosis. In breast cancer, high expression of KLHL7 is linked to higher histological grades, estrogen receptor (ER)-negative or human epidermal growth factor receptor 2 (HER-2)-positive tumors, and triple-negative breast cancer (TNBC), and patients with high KLHL7 expression have shorter survival times. In gastric cancer, silencing KLHL7 gene expression can inhibit the proliferation, migration, and invasion of gastric cancer cells and has shown tumor-suppressive effects in in vivo models. Moreover, KLHL7 is highly expressed in colorectal cancer and ovarian cancer, among others, and is significantly associated with low patient survival rates.