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KLRG1 Rekombinanter Antikörper

KLRG1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242327B12

Kat-Nr. : 84785-4-PBS

Synonyme

MAFA, Killer cell lectin-like receptor subfamily G member 1, ITIM-containing receptor MAFA-L, C-type lectin domain family 15 member A, CLEC15A

Filter:
  • Western Blot (WB) analysis of various lysates using KLRG1 Recombinant antibody (84785-4-RR)

    WB analysis using 84785-4-RR (same clone as 84785-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84785-4-RR (KLRG1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84785-4-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using KLRG1 Recombinant antibody (84785-4-RR)

    WB analysis using 84785-4-RR (same clone as 84785-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84785-4-RR (KLRG1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84785-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84785-4-PBS bindet in WB, Indirect ELISA KLRG1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name killer cell lectin-like receptor subfamily G, member 1
Berechnetes Molekulargewicht22 kDa
Beobachtetes Molekulargewicht30-38 kDa
GenBank-ZugangsnummerNM_005810.4
Gene symbol KLRG1
Gene ID (NCBI) 10219
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role in NK- and T-cell function (PMID: 19009530; 20373518). Because of the glycosylation and disulfide bonds of the KLRG1 proteins, the observed molecular weights are typically 30-38 kDa (PMID: 17404256).