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KREMEN1 Polyklonaler Antikörper

KREMEN1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25434-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using KREMEN1 Polyclonal antibody (25434-1-AP)

    WB analysis using 25434-1-AP (same clone as 25434-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25434-1-AP (KREMEN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25434-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25434-1-PBS bindet in WB, Indirect ELISA KREMEN1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen KREMEN1 fusion protein Ag22092
Vollständiger Name kringle containing transmembrane protein 1
Berechnetes Molekulargewicht 473 aa, 52 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC063787
Gene symbol KREMEN1
Gene ID (NCBI) 83999
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Kringle containing transmembrane protein 1 (KREMEN1, also known as KRM1, ECTD13, and KREMEN) is a transmembrane receptor located in the membrane. During the development of various organs, including the nervous system, limbs, and liver, KREMEN1 synergizes with the Dkk proteins to inhibit Wnt signaling (PMID: 18505822). KREMEN1 has been reported as a tumor suppressor, preventing cancer cell survival in a ligand-poor environment (PMID: 31069116). Variations and mutations of KREMEN1 have been associated with ectodermal dysplasia and Hand-foot-and-mouth disease (PMID: 34028942; 31911601).