Kindlin 2 Polyklonaler Antikörper

Kindlin 2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29911-1-PBS

Synonyme

FERMT2, FERMT 2, mig 2, Kindlin-2, kindlin2

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  WB analysis using 29911-1-AP (same clone as 29911-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29911-1-AP (Kindlin 2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human normal colon slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:1200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human normal colon slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:1200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 29911-1-AP (same clone as 29911-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29911-1-AP (Kindlin 2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29911-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

29911-1-PBS bindet in WB, IHC, Indirect ELISA Kindlin 2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Kindlin 2 fusion protein Ag31795
• Vollständiger Name: fermitin family homolog 2 (Drosophila)
• Berechnetes Molekulargewicht: 680 aa, 78 kDa
• Beobachtetes Molekulargewicht: 78 kDa
• GenBank-Zugangsnummer: BC017327
• Gene symbol: Kindlin 2
• Gene ID (NCBI): 10979
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

FERMT2, also named as KIND2, MIG2, PLEKHC1, MIG-2 and Kindlin-2, belongs to the kindlin family. There are three FERMT2 isoforms that participate in the connection between extracellular matrix (ECM) adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. FERMT2 recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Variable expression in human cancers and mesenchymal cancer invasion are now linked with FERMT2, which may plays important role in carcinormas development.