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Kir2.1 Polyklonaler Antikörper

Kir2.1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19965-1-PBS

Synonyme

KCNJ2, IRK-1, IRK1, IRK 1, hIRK1

Filter:
  • Western Blot (WB) analysis of A549 cells using Kir2.1 Polyclonal antibody (19965-1-AP)

    WB analysis of A549 using 19965-1-AP (same clone as 19965-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 19965-1-AP (Kir2.1 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19965-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A549 cells using Kir2.1 Polyclonal antibody (19965-1-AP)

    WB analysis of A549 using 19965-1-AP (same clone as 19965-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 19965-1-AP (Kir2.1 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19965-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using Kir2.1 Polyclonal antibody (19965-1-AP)

    IHC staining of human brain using 19965-1-AP (same clone as 19965-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 19965-1-AP (Kir2.1 antibody at dilution of 1:50. This data was developed using the same antibody clone with 19965-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

19965-1-PBS bindet in WB, Indirect ELISA Kir2.1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name potassium inwardly-rectifying channel, subfamily J, member 2
Berechnetes Molekulargewicht 48 kDa
Beobachtetes Molekulargewicht 50 kDa, 60 kDa
GenBank-ZugangsnummerNM_000891
Gene symbol Kir2.1
Gene ID (NCBI) 3759
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

KCNJ2, also named as HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7 and SQT3, belongs to the inward rectifier-type potassium channel family. KCNJ2 probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ2 can be blocked by extracellular barium or cesium. Defects in KCNJ2 are the cause of long QT syndrome type 7 (LQT7). Defects in KCNJ2 are the cause of short QT syndrome type 3 (SQT3). The antibody recognizes the C-term of KCNJ2.