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Kir6.2 Polyklonaler Antikörper

Kir6.2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16920-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of rat heart tissue using Kir6.2 Polyclonal antibody (16920-1-AP)

    WB analysis of rat heart using 16920-1-AP (same clone as 16920-1-PBS)

    rat heart tissue were subjected to SDS PAGE followed by western blot with 16920-1-AP (Kir6.2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16920-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat skeletal muscle tissue using Kir6.2 Polyclonal antibody (16920-1-AP)

    WB analysis of rat skeletal muscle using 16920-1-AP (same clone as 16920-1-PBS)

    rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 16920-1-AP (Kir6.2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16920-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using Kir6.2 Polyclonal antibody (16920-1-AP)

    WB analysis of HepG2 using 16920-1-AP (same clone as 16920-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 16920-1-AP (KCNJ11 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16920-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human heart tissue using Kir6.2 Polyclonal antibody (16920-1-AP)

    WB analysis of human heart using 16920-1-AP (same clone as 16920-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 16920-1-AP (KCNJ11 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16920-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16920-1-PBS bindet in WB, Indirect ELISA Kir6.2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Kir6.2 fusion protein Ag10262
Vollständiger Name potassium inwardly-rectifying channel, subfamily J, member 11
Berechnetes Molekulargewicht 390 aa, 44 kDa
Beobachtetes Molekulargewicht 48 kDa
GenBank-ZugangsnummerBC064497
Gene symbol Kir6.2
Gene ID (NCBI) 3767
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Kir6.2 (also known as BIR or IKATP), encoded by the KCNJ11 gene, is the pore-forming unit of the ATP-sensitive K+ channel, an inward-rectifier potassium ion channel. Kir6.2 is controlled by G-proteins and is found associated with the sulfonylurea receptor (SUR) to constitute the ATP-sensitive K+ channel. The KCNJ11 gene is located at 11p15.1 and has no intron. Mutations in KCNJ11 are a cause of familial PHHI, an autosomal recessive disorder characterized by unregulated ins secretion. Defects in KCNJ11 may also contribute to autosomal dominant non-ins-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM).