L1CAM/CD171 Rekombinanter Antikörper

L1CAM/CD171 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250101F8

Kat-Nr. : 98510-1-RR

Synonyme

L1cam, N-CAM-L1, CAML1, CD171, N CAM L1

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  FC experiment of Transfected HEK-293T using 98510-1-RR

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 98510-1-RR

  1x10^6 293T cells or L1CAM/CD171 transfected 293T cells were surface stained with 0.25 ug Anti-Mouse L1CAM/CD171 Rabbit RecAb (98510-1-RR, Clone: 250101F8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98510-1-RR bindet in FC L1CAM/CD171 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: L1CAM/CD171 fusion protein Eg3022
• Vollständiger Name: L1 cell adhesion molecule
• Berechnetes Molekulargewicht: 141 kDa
• GenBank-Zugangsnummer: N/A
• Gene symbol: L1cam
• Gene ID (NCBI): 16728
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail (PMID: 3412448; 22796939). L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts (PMID: 3412448; 10767310). L1CAM is overexpressed in many human cancers and is often associated with bad prognosis (PMID: 27267927; 26111503).