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L3HYPDH Polyklonaler Antikörper

L3HYPDH Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33146-1-PBS

Synonyme

C14orf149, EC:4.2.1.77, Trans-3-hydroxy-L-proline dehydratase, Trans-L-3-hydroxyproline dehydratase

Filter:
  • Western Blot (WB) analysis of various lysates using L3HYPDH Polyclonal antibody (33146-1-AP)

    WB analysis using 33146-1-AP (same clone as 33146-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33146-1-AP (L3HYPDH antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33146-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33146-1-PBS bindet in WB, Indirect ELISA L3HYPDH und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen L3HYPDH fusion protein Ag37121
Vollständiger Name chromosome 14 open reading frame 149
Berechnetes Molekulargewicht38 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC012131
Gene symbol C14orf149
Gene ID (NCBI) 112849
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Trans-3-hydroxy-L-proline dehydratase (L3HYPDH) is an enzyme that catalyzes the conversion of trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme is involved in the degradation of dietary proteins containing trans-3-hydroxy-L-proline, such as collagen IV. Additionally, L3HYPDH has been identified as an interferon-stimulated gene (ISG) with antiviral activity, particularly against viruses like EV71 (PMID: 35891782). It also plays a role in the genetic regulation of working memory and has been implicated in the mitochondrial pathway associated with autism spectrum disorder (PMID: 32490597).